First results of 3D human sebaceous glands technology for skin care applications
BASF and CTIBiotech developed a research on 3D tissue models for the development and testing of bio-actives for skin care applications which they presented at NYSCC Cosmetic Congress.
First of all, it must be said that sebaceous glands help the skin stay moist and protect it against external influences such as harsh weather, pollution, and microbial assaults: The oily or waxy
matter that these microscopic, exocrine glands secrete – called sebum – lubricates and softens the skin and hair.
Simply put, experts used CTIBiotech’s 3D human sebaceous gland technology to improve BASF’s 3D skin model portfolio. If BASF’s experts have a good understanding of sebaceous gland metabolism, the new 3D technology provides a powerful platform for skin care researchers wishing to study the function of sebaceous glands, in relation to a range of age-related, microbial and inflammatory skin disorders.
BASF’s project lead Dr. Sabine Pain explained that “compared to current in vitro methods, the 3D models developed by CTIBiotech allow analysis more in touch with human physiology and sebaceous gland metabolism.” That’s the reason why they were happy to use their technology. They were able to accelerate the development of innovative and highly reliable ingredients for the skin care market.
“Because of their experience and expertise in developing solutions for the dermo-cosmetics market, BASF understands the benefits of collaborating with tissue engineering experts,” added Professor Colin McGuckin, Chief Scientific Officer and President of CTIBiotech. “The next evolution of the sebaceous gland model will be based on a 3D bio-printing technology that allows us to fully reproduce micro-glands into a full thickness skin model, in vitro.”
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