Joseph DeSimone’s work continues to go beyond Carbon’s DLS 3D printing. The entrepreneur and scientist is behind the development of high-resolution 3D-printed microneedle technology.
This solution would improve the resolution and precision of 3D printed microfluidic devices by continuously feeding fresh resin into negative spaces during printing, preventing over-curing and ensuring a more accurate structure.
The concept’s official name is injection CLIP (iCLIP). The method was introduced last year as an opportunity to print with multiple types of resin over the course of the printing process – each new resin simply requires its own syringe.
PinPrint’s innovation is a next-generation microneedle patch designed to deliver vaccines and active agents intradermally, replacing the need for traditional injections. “By integrating high-resolution 3D printing with advanced drug delivery, we’re redefining the patient experience across therapeutic and cosmetic categories—offering a new standard for precision, personalization, and comfort,” said Dr. DeSimone.
This strategic investment aligns with Continuity’s mission to advance targeted delivery technologies. The company is currently developing implanted nanofluidic platforms through its work with the Grattoni Lab at Houston Methodist Hospital, with capabilities for extended, zero-order release.
“This investment allows us to expand from implanted nanofluidic systems to a non-implanted microfluidic platform,” said Ramakrishna Venugopalan, PhD, Co-Founder and CEO of Continuity Biosciences. “It opens the door for more effective delivery of dermatologic, aesthetic, and cosmetic agents directly into the dermis.”
The investment expands Continuity’s footprint beyond therapeutic delivery into aesthetic and cosmetic applications, enhancing long-term strategic value. As part of the transaction, Dr. Venugopalan will join PinPrint’s Board of Directors. “We welcome Krishna to the Board”, said Renee Ryan, MBA, Co-Founder and CEO of PinPrint, Inc. “His domain expertise and strategic leadership will be instrumental, as we redefine what’s possible in drug and vaccine delivery.”
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