The project aims to fill the critical gap created by the lack of effective treatments currently available for Tendinopathies and osteoarthritis.
The TRIANKLE consortium – made up of 12 European organisations, will develop 3D bioprinted personalized scaffolds for tissue regeneration of ankle joints. This ambitious research project in regenerative medicine comes with an overall budget of €5.9M and will be developed over 4 years, starting January 2021.
The consortium aims to create innovative personalized collagen- and gelatine-based implants manufactured with 3D technology for patients with tendinopathies such as Achilles tendon partial ruptures and cartilage injuries.
A common and expensive health problem
Tendinopathies and osteoarthritis (OA) are extremely common, especially among the elderly, women, and professional athletes. In addition to quality of life, both conditions substantially impact healthcare systems of economies worldwide. For example, OA costs €76.5 billion in EU every year, while tendinopathies have an estimated expenditure above €140 billion.
The project aims to fill the critical gap created by the lack of effective treatments currently available. None of the existing surgical or non-surgical alternatives have provided a successful long-term solution for patients, and often the treated tissues do not recover their complete strength and functionality.
In this context, TRIANKLE’s objectives will be to reduce recovery time by 50% and, at the same time, increase the functionality ratios of the injured tissue by 10%-15%.
Organizations that will work on the TRIANKLE project
12 organisations from 5 different countries (Germany, Spain, Sweden, the Netherlands, and the United Kingdom) are part of the TRIANKLE consortium.
The partnership includes one industry partner (Naturin Viscofan GmbH), three SMEs (CELLINK AB, Cambridge Nanomaterials Technology, and Gradocell SL), two research centres (Institute for Interfacial Engineering and Biotechnology IGB and Acondicionamiento Tarrasense Associacion), three universities (University of Stuttgart, Universidad del País Vasco, and Eindhoven University of Technology), two non-profit organisations (Futbol Club Barcelona Asociacion FCB and Osteoarthritis Foundation International OAFI), and one healthcare institution (Fundacio Clinic per a la Recerca Biomedica).
The TRIANKLE project coordinator is Naturin Viscofan GmbH.
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